Set Sail for Adventure: Your One-Day Cruise from Tampa to Key West

Thinking about a one-day cruise from Tampa to Key West? Whether you’re a travel enthusiast, a cruise lover, or someone just curious about exploring the southernmost gem of the United States, this guide is for you! Tampa’s world-class cruises and waterfront charm make it an ideal starting point for an incredible Key West getaway.

From breathtaking views of the Gulf of Mexico to wandering the paradise of Key West, we’re covering everything you need to know to turn your cruise into the perfect day. So grab your sunscreen, because here we go!

Tampa to Key West Cruise Options

Ah, Tampa! With its rich history, fantastic attractions like Busch Gardens and the Tampa Riverwalk, and proximity to the Gulf Coast, it’s a dreamy departure point for travelers. But what exactly are your best travel options for a Key West getaway? Let’s break it down.

1. Round-Trip Cruises with Port Stops in Key West

Many luxury cruise lines departing from Port Tampa Bay include Key West as part of their itinerary. These trips, offered by Royal Caribbean Cruises and Carnival Cruise Line, often stop at multiple epic destinations like Grand Cayman, Cozumel, or Costa Maya.

Here’s the kicker though… depending on your cruise, you might only get 4 to 8 hours in Key West. While it’s not enough time to sip a margarita in every Duval Street bar, you’ll still have a great time soaking in the main highlights. Think of it as a sweet taste of Key West, and hey, there’s always the next cruise vacation!

2. The Key West Express Ferry

For the impatient wanderer (aka me 99% of the time), there’s the Key West Express ferry! While it doesn’t technically depart from Tampa, it’s only a short drive to Fort Myers or Marco Island (under three hours). Once aboard, this high-speed ferry zips you across the open water, straight to the epic shores of Key West.

Insider Tip: The ferry operates year-round and offers snacks, cocktails, and beautiful views of the Florida Keys’ shallow waters, with the wind in your hair and palm trees on the horizon. Total travel time is about three and a half hours one way, so pack a good playlist and prepare for marine life sightings!

3. Drive, Stop, and Hop!

Not into ferries or cruise ships? Drive from Tampa to Key West. It’s roughly 7 hours of picturesque Florida scenery, including bridges and views over beautiful beaches on the west coast of Florida. For a little more fun, stop at towns like Ft. Myers Beach, St. Petersburg, or Ybor City and absorb a taste of authentic Florida Cracker cuisine along the way. Trust us, the food and local attractions make it worth the ride!

What to Do Once You Arrive in Key West

Welcome to Key West, the wandering paradise you didn’t know you needed! Here’s how to make the most of your time, whether you’re on a one-day excursion or an extended trip.

1. Iconic Must-Sees

• Southernmost Point: Snap a pic at the buoy and document your I’ve-been-to-the-southernmost-tip-of-the-USA adventure. It’s a touristy must!
• Duval Street: The beating heart of Key West. Explore upscale boutique stores, do a pub crawl, sip on rum cocktails, or chill to some live music.
• Ernest Hemingway Home and Tennessee Williams Museum: Peek into the lives of literary legends who called Key West home. Hemingway’s six-toed cats are kind of a big deal.

Check out our Free Happy Hour Guide – Here!

2. Dive into the Water

Key West is surrounded by shallow waters teeming with sea turtles, coral reefs, and marine life. Whether it’s scuba diving, snorkeling, or a glass-bottom boat tour, don’t leave without experiencing its underwater magic.

• Dry Tortugas National Park & Fort Jefferson: This remote gem is home to pristine waters, vibrant coral reefs, and centuries-old history. But here’s the catch—you’ll need a full day for this adventure, starting with a Yankee Freedom ferry ride. It’s the ultimate escape if you’ve got more than one day to spare.

3. Eat, Drink, and Be Key-West-Centric

• Key Lime Pie Crawl: Have a slice (or three) at local favorites like Kermit’s or Blue Heaven. It’s a taste of Key West you won’t forget.
• Local Raw Bars with Fresh Seafood: Don’t miss places like Half Shell Raw Bar or Thirsty Mermaid for authentic Florida flavors straight from the ocean.

Other Adventures Along the Way

From Tampa:

Before you set sail, take some time to explore:

• Tampa Riverwalk: Lined with restaurants, bars, and scenic spots.
• Tampa Museum of Art & Tampa Bay History Center: Delve into interactive exhibits and get lost in the city’s fascinating backstory.
• Curtis Hixon Waterfront Park: Relax under the sunshine before leaving the Sunshine State.

On the Gulf Coast:

If you’re driving or ferrying via Ft. Myers Beach or Marco Island, marvel at the beautiful beaches, or stop by Caladesi Island State Park for some off-the-beaten-path tranquility.

Best Time and Tips for Your Key West Adventure

Best Time to Visit

Planned your adventure during hurricane season (gulp)? Don’t fret! Winter months and early spring are the best times to visit Key West for cool breezes and sunny vibes. Avoid cold fronts during the peak of summer as it gets pretty hot and humid. Pack light and don’t forget comfy shoes for all the walking you’ll do!

Insider Tips

• Book Shore Excursions Early: If you’re cruising, snag your shore excursion tickets upon boarding to make the most of your Key West layover.
• Plan Around Famous Works of Weather (Hurricanes): Florida’s weather can be unpredictable, so check forecasts often.
• Be Flexible with Boat Trips: Changes in the time of year and tide conditions might affect ferry schedules. Always double-check before booking.

Why You’ll Want to Go Back

Here’s the thing about Key West. Even if you spend just one day here, you’ll quickly realize it’s not nearly enough to explore everything the island has to offer. Between the lush tropical landscapes, the friendly vibe, and the countless great options for adventure, you’ll immediately be itching to return.

Don’t say we didn’t warn you! One day is just a tempting teaser of paradise.